·         Hsin-Hou Chang, Hu ST, Huang TF, Chen SH, Lee YHW and Szecheng J Lo. (1993) Rhodostomin, an RGD-containing peptide expressed from a synthetic gene in Escherichia coli, facilitates the attachment of human hepatoma cells. Biochem. Biophys. Res. Commun.190,242-249. 

·         Hsin-Hou Chang, Wei-Jern Tsai, and Szecheng J Lo. (1997) Glutathione S-transferase-rhodostomin fusion proteins inhibit platelet aggregation and induce platelet shape change. Toxicon 35,195-204. 

·         Hsin-Hou Chang, Chang CP, Chang JC, Dung SZ and Szecheng J Lo. (1997) Application of Recombinant Rhodostomin in Studying Cell Adhesion. J. Biomed. Sci.4,235-243. 

·         Hsin-Hou Chang and Szecheng J Lo. (1998) Full-spreading platelets induced by the recombinant rhodostomin are via binding to integrins and correlated with FAK phosphorylation. Toxicon 36,1087-1099.

·         Hsin-Hou Chang, S-Y Sheu, and Szecheng J Lo. (1999) Expression of foreign antigens on Escherichia coli surface by an outer membrane protein TraT. J. Biomed. Sci.6,64-70.

·         Hsin-Hou Chang, Chi-Hung Lin, and Szecheng J Lo. (1999) Recombinant rhodostomin substrates induce transformation and active calcium oscillation in human platelets. Exp. Cell Res.250,387-400.250,387-400. 

·         Hsin-Hou Chang, Ko-Nien Shih, and Szecheng J Lo. (2000) Receptor-mediated endocytosis as a selection force to enrich bacteria expressing rhodostomin on surface. J. Biomed. Sci.7,42-50.

·         Rong-Hwa Shyu, Men-Fang Shaio, Shiao-Shek Tang, Huey-Fen Shyu, Chi-Feng Lee, Meng-Hung Tsai, Hsin-Hsien Huang, Jiunn-Jye Wey, Jan-Ling Huang, and Hsin-Hou Chang*. (2000). DNA vaccination with the Fragment C of botulinum neurotoxin type A elicits protective immunity in mice. J. Biomed. Sci.7,50-57.  

·         Hsin-Hou Chang, and Szecheng J Lo. (2000) Modification with a phosphorylation tag of PKA in the TraT-based display vector of Escherichia coli. J. Biotechnology.10,115-122. 

·         Chih-Pei Chang, Jui-Chin Chang, Hsin-Hou Chang, Wei-Jern Tsai, and Szecheng J Lo. (2001) Positional importance of Pro53 adjacent to the Arg49-Gly50-Asp51 sequence of rhodostomin in binding to integrin alphaIIbbeta3. Biochem. J.357,57-64.

·         Hsin-Hou Chang*, Huey-Fen Shyu, Yo-Ming Wang, Der-Shan Sun, Rong-Hwa Shyu, Shiao-Shek Tang, and Yao-Shine Huang (2002). Facilitation of Cell Adhesion by Immobilized Dengue Viral Nonstructural Protein 1 (NS1): Arginine-Glycine-Aspartic Acid Structural Mimicry within the Dengue Viral NS1 Antigen. J. Infect. Dis.186,743-751.   (Impact factor: 5.99)

·         Hsin-Hou Chang*, Jyh-Hwa Kau, You-Ming Wang, Der-Shan Sun, Szecheng J. Lo. (2003). Cell-adhesion and morphological changes are not sufficient to support anchorage-dependent cell growth via non-integrin-mediated attachment. Cell Biol. Int. 27,123-133. 

·         Der-Shan Sun and Hsin-Hou Chang (2003). Differential regulation of JNK in caspase-3 dependent apoptosis of MPP+ treated primary cortical neurons and untreated control cells. Cell Biol. Int. 27, 769-777.

·         Jyh-Hwa Kau, Der-Shan Sun, Wei-Jern Tsai, Huey-Fen Shyu, Hsin-Hsien Huang, Hung-Chi Lin, and Hsin-Hou Chang* (2005). Anti-platelet activities of anthrax lethal toxin are associated with suppressed p42/44 and p38 mitogen-activated protein kinase pathways in the platelets. J. Infect. Dis. 192, 1465-1474.    (Impact factor: 5.99)

·         Szecheng J. Lo and Hsin-Hou Chang  (2005) Recombinant snake disintegrins used for mammalian integrin study. Toxin Rev. 24,95-111.

·         Der-Shan Suna, Szecheng J. Lo, Chi-Hung Lin, Mei-Shiuan Yu, Ching-Yi Huang, Yao-Fong Chen and Hsin-Hou Chang* (2005). Calcium oscillation and phosphatidylinositol 3-kinase positively regulate integrin aIIbb3-mediated outside-in signaling. J. Biomed. Sci. 12, 321-333.    

·         Jui-Chin Chang, Hsin-Hou Chang, Chien-Ting Lin and Szecheng J. Lo. (2005). The integrin a6b1 modulation of PI3K and Cdc42 activities induces dynamic filopodium formation in human platelets. J. Biomed. Sci. 12, 881-898.

·         Der-Shan Sun, Szecheng J. Lo, Wei-Jern Tsai, Chi-Hung Lin, Mei-Shiuan Yu, Yao-Fong Chen and Hsin-Hou Chang* (2005). PI3-kinase is essential for ADP-stimulated integrin aIIbb3-mediated platelet calcium oscillation, implications for P2Y receptor pathways in integrin aIIbb3-initiated signaling cross-talks. J. Biomed. Sci. 12, 937-948.   

·         Hsin-Hou Chang, Mei-Fang Tsai, Chia-Pei Chung, Po-Kong Chen, Hsin-I Hu, Jyh-Hwa Kau, Hsin-Hsien Huang, Hung-Chi Lin and Der-Shan Sun. (2006). Single-step purification of recombinant anthrax lethal factor from periplasm of Escherichia coli. J Biotechnol 277-285.

·         Ming-Show Wong, Wen-Chen Chu, Der-Shan Sun, Hsuan-Shun Huang, Jiann-Hwa Chen, Pei-Jane Tsai, Nien-Tsung Lin, Mei-Shiuan Yu, Shang-Feng Hsu, Shih-Lien Wang, and Hsin-Hou Chang* (2006). Visible-light-induced bactericidal activity of a nitrogen-doped titanium photocatalyst against human pathogens. Appl Environ Microbiol 72, 6111-6116.  

·         Hsin-Hou Chang* and Szecheng J. Lo (2007). Snake venom disintegrin rhodostomin served as a molecular tool to dissect the integrin function. Toxin Reviews 26, 189-202.  

·         Shu-Rung Chang, Kung-Jiun Wang, Yan-Feng Lu, Lii-Jia Yang, Wei-Jie Chen, Yu-Hsiang Lin, Hsin-Hou Chang, and Shih-Lien Wang (2007). Characterization of early gamma interferon (IFN-gamma) expression during murine listeriosis: identification of NK1.1(+) CD11c(+) cells as the primary IFN-gamma-expressing cells. Infect Immun 75, 1167-1176.

·         Der-Shan Sun, Chwan-Chuen King, Hsuan-Shun Huang, Yung-Luen Shih, Chin-Cheng Lee, Wei-Jern Tsai, Cheng-Ching Yu and Hsin-Hou Chang* (2007). Antiplatelet autoantibodies elicited by dengue virus non-structural protein 1 cause thrombocytopenia and mortality in mice. J Thromb Haemost 5, 2291-2299.    (Impact factor: 5.72)

·         Chia-Liang Cheng, Der-Shan Sun, Wen-Chen Chu, Yao-Hsuan Tseng, Han-Chen Ho, Jia-Bin Wang, Pei-Hua Chung, Jiann-Hwa Chen, Pei-Jane Tsai, Nien-Tsung Lin, Mei-Shiuan Yu and Hsin-Hou Chang* (2009). The effects of the bacterial interaction with visible-light responsive titania photocatalyst on the bactericidal performance. J Biomed Sci 16, 7.   

·         Jyh-Hwa Kau, Der-Shan Sun, Hsin-Hsien Huang, Ming-Show Wong, Hung-Chi Lin, Hsin-Hou Chang* (2009). Role of visible light-activated photocatalyst on the reduction of anthrax spore-induced mortality in mice. PLoS ONE 4, e4167.  

·         Ming-Show Wong, Der-Shan Sun, Hsin-Hou Chang* (2010).  Bactericidal Performance of Visible-Light Responsive Titania Photocatalyst with Silver Nanostructures. PLoS ONE 5, e10394  

·         Hsuan-Shun Huang, Der-Shan Sun, Te-Sheng Lien and Hsin-Hou Chang* (2010). Dendritic cells modulate platelet activity in IVIg-mediated amelioration of ITP in mice. Blood, 116, 5002-9. (Impact factor: 10.45).

·         Jyh-Hwa Kau, Der-Shan Sun, Hsuan-Shun Huang, Te-Sheng Lien, Hsin-Hsien Huang, Hung-Chi Lin, Hsin-Hou Chang* (2010). Sublethal Doses of Anthrax Lethal Toxin on the Suppression of Macrophage Phagocytosis PLoS ONE 5, e14289.

·         Je-Wen Liou, Ming-Hui Gu, Yen-Kai Chen, Wen-Yi Chen, Yi-Cheng Chen, Yao-Hsuan Tseng, Yu-Jiun Hung, Hsin-Hou Chang* (2011). Visible Light Responsive Photocatalyst Induces Progressive and Apical-Terminus Preferential Damages on Escherichia coli Surfaces. PLoS ONE 6, e19982.

·         Wen-Ku Chang, Der-Shan Sun, Hao Chan, Pai-Tsang Huang, Wen-Shiang Wu, Ching-Hui Lin, Yao-Hsuan Tseng, Yi-Hung Cheng, Chun-Chieh Tseng and Hsin-Hou Chang* (2011). Visible light responsive core-shell structured In2O3@CaIn2O4 photocatalyst with superior bactericidal property and biocompatibility. Nanomedicine: Nanotechnology, Biology and Medicine, 2012; 8:609-17. (Impact factor: 6.16).

·         Kau JH, Shih YL, Lien TS, Lee CC, Huang HH, Lin HC, Sun DS, Chang HH*. Activated protein C ameliorates Bacillus anthracis lethal toxin-induced lethal pathogenesis in rats. J Biomed Sci 2012; 19:98.

·         Liou JW, Chang HH*. Bactericidal effects and mechanisms of visible light-responsive titanium dioxide photocatalysts on pathogenic bacteria. Arch Immunol Ther Exp (Warsz) 2012; 60:267-75 (Invited review).

·         Huang HS, Chang HH*. Platelets in Inflammation and Immune Modulations: Functions Beyond Hemostasis. Arch Immunol Ther Exp (Warsz) 2012:443-51 (Invited review).

·         Lin YC, Tsai LW, Perevedentseva E, Chang HH, Lin CH, Sun DS, Lugovtsov AE, Priezzhev A, Mona J, Cheng CL. The influence of nanodiamond on the oxygenation states and micro rheological properties of human red blood cells in vitro. Journal of Biomedical Optics 2012; 17:101512.

·         Chen YL, Chen YS, Chan H, Tseng YH, Yang SR, Tsai HY, Liu HY, Sun DS, Chang HH*. The use of nanoscale visible light-responsive photocatalyst TiO2-Pt for the elimination of soil-borne pathogens. PLoS One 2012; 7:e31212.

·         Chang HH, Wang TP, Chen PK, Lin YY, Liao CH, Lin TK, Chiang YW, Lin WB, Chiang CY, Kau JH, Huang HH, Hsu Hl, Liao CY, Sun DS. Erythropoiesis suppression is associated with anthrax lethal toxin-mediated pathogenic progression. PLoS One 2013; 8:e71718.

·         Tseng YH, Sun DS, Wu WS, Chan H, Syue MS, Ho HC, Chang HH*. Antibacterial performance of nanoscaled visible-light responsive platinum-containing titania photocatalyst in vitro and in vivo. Biochim Biophys Acta 2013; 1830:3787-95.

·         Chen PK, Chang HH, Lin GL, Wang TP, Lai YL, Lin TK, Hsieh MC, Kau JH, Huang HH, Hsu HL, Liao CY, Sun DS. Suppressive effects of anthrax lethal toxin on megakaryopoiesis. PLoS One 2013; 8:e59512.

·         Chang HH, Chiang YW, Lin TK, Lin GL, Lin YY, Kau JH, Huang HH, Hsu HL, Wang JH, Sun DS. Erythrocytic mobilization enhanced by the granulocyte colony-stimulating factor is associated with reduced anthrax-lethal-toxin-induced mortality in mice. PLoS One 2014; 9:e111149.

·         Chang HH, Chen PK, Lin GL, Wang CJ, Liao CH, Hsiao YC, Dong JH, Sun DS. Cell adhesion as a novel approach to determining the cellular binding motif on the severe acute respiratory syndrome coronavirus spike protein. J Virol Methods 2014; 201:1-6.

·         Chen YS, Shieh WJ, Goldsmith CS, Metcalfe MG, Greer PW, Zaki SR, Chang HH, Chan H, Chen YL. Alteration of the phenotypic and pathogenic patterns of Burkholderia pseudomallei that persist in a soil environment. Am J Trop Med Hyg 2014; 90:469-79.

·         Sun DS, Chang YC, Lien TS, King CC, Shih YL, Huang HS, Wang TY, Li CR, Lee CC, Hsu PN, Chang HH*. Endothelial Cell Sensitization by Death Receptor Fractions of an Anti-Dengue Nonstructural Protein 1 Antibody Induced Plasma Leakage, Coagulopathy, and Mortality in Mice. J Immunol 2015; 195:2743-53. (Impact factor: 4.922).

·         Lien TS, Sun DS, Chang CM, Wu CY, Dai MS, Chan H, Wu WS, Su SH, Lin YY, Chang HH*. Dengue virus and antiplatelet autoantibodies synergistically induce haemorrhage through Nlrp3-inflammasome and FcgammaRIII. Thromb Haemost 2015; 113:1060-70. (Impact factor: 4.98)

·         Wong MS, Chen CW, Hsieh CC, Hung SC, Sun DS, Chang HH*. Antibacterial property of Ag nanoparticle-impregnated N-doped titania films under visible light. Sci Rep 2015; 5:11978. (Impact factor: 5.58)

·         Wu MS, Sun DS, Lin YC, Cheng CL, Hung SC, Chen PK, Yang JH, Chang HH*. Nanodiamonds protect skin from ultraviolet B-induced damage in mice. J Nanobiotechnology 2015; 13:35.

·         Sun DS, Lee PC, Kau JH, Shih YL, Huang HH, Li CR, Lee CC, Wu YP, Chen KC, Chang HH*. Acquired coagulant factor VIII deficiency induced by Bacillus anthracis lethal toxin in mice. Virulence 2015; 6:466-75.

·         Hu HI, Chang HH, Sun DS. Differential regulation of caspase-2 in MPP(+)-induced apoptosis in primary cortical neurons. Exp Cell Res 2015; 332:60-6.

·         Chen PK, Lin GL, Chang HH, Sun DS. Megakaryocytic differentiation of mouse embryonic stem cells via coculture with immortalized OP9 stromal cells. Exp Cell Res 2015 Oct 7. pii: S0014-4827(15)30108-7. doi: 10.1016/j.yexcr.2015.10.002. [Epub ahead of print].