Publications:
·
Hsin-Hou Chang, Hu ST, Huang TF,
Chen SH, Lee YHW and Szecheng J Lo. (1993) Rhodostomin,
an RGD-containing peptide expressed from a synthetic gene in Escherichia
coli, facilitates the attachment of human hepatoma cells. Biochem.
Biophys. Res. Commun.190,242-249.
·
Hsin-Hou Chang, Wei-Jern Tsai, and Szecheng J
Lo. (1997)
Glutathione S-transferase-rhodostomin fusion proteins inhibit platelet
aggregation and induce platelet shape change. Toxicon
35,195-204.
·
Hsin-Hou
Chang,
Chang CP, Chang JC, Dung SZ and Szecheng J Lo. (1997)
Application of Recombinant Rhodostomin in Studying Cell Adhesion. J.
Biomed. Sci.4,235-243.
·
Hsin-Hou Chang and Szecheng J Lo. (1998) Full-spreading platelets
induced by the recombinant rhodostomin are via binding to integrins and
correlated with FAK phosphorylation. Toxicon
36,1087-1099.
·
Hsin-Hou Chang, S-Y Sheu, and Szecheng J Lo. (1999)
Expression of foreign antigens on Escherichia coli surface by an
outer membrane protein TraT. J.
Biomed. Sci.6,64-70.
·
Hsin-Hou
Chang,
Chi-Hung Lin, and Szecheng J Lo. (1999)
Recombinant rhodostomin substrates induce transformation and active calcium
oscillation in human platelets. Exp.
Cell Res.250,387-400.250,387-400.
·
Hsin-Hou Chang, Ko-Nien Shih, and Szecheng J
Lo. (2000)
Receptor-mediated endocytosis as a selection force to enrich bacteria
expressing rhodostomin on surface. J.
Biomed. Sci.7,42-50.
·
Rong-Hwa Shyu, Men-Fang Shaio, Shiao-Shek Tang, Huey-Fen Shyu,
Chi-Feng Lee, Meng-Hung Tsai, Hsin-Hsien
Huang, Jiunn-Jye Wey, Jan-Ling Huang, and Hsin-Hou Chang*. (2000). DNA vaccination
with the Fragment C of botulinum neurotoxin type A elicits protective immunity
in mice. J.
Biomed. Sci.7,50-57.
·
Hsin-Hou Chang, and Szecheng J Lo. (2000) Modification with a
phosphorylation tag of PKA in the TraT-based display
vector of Escherichia coli. J.
Biotechnology.10,115-122.
·
Chih-Pei Chang, Jui-Chin Chang, Hsin-Hou
Chang, Wei-Jern Tsai, and Szecheng
J Lo. (2001) Positional importance of Pro53 adjacent to the Arg49-Gly50-Asp51
sequence of rhodostomin in binding to integrin alphaIIbbeta3. Biochem.
J.357,57-64.
·
Hsin-Hou Chang*, Huey-Fen Shyu, Yo-Ming Wang, Der-Shan Sun,
Rong-Hwa Shyu, Shiao-Shek Tang, and Yao-Shine Huang (2002).
Facilitation of Cell Adhesion by Immobilized Dengue Viral Nonstructural Protein
1 (NS1): Arginine-Glycine-Aspartic Acid Structural Mimicry within the Dengue
Viral NS1 Antigen. J.
Infect. Dis.186,743-751. (Impact factor: 5.99)
·
Hsin-Hou Chang*,
Jyh-Hwa Kau, You-Ming Wang, Der-Shan Sun, Szecheng J. Lo. (2003).
Cell-adhesion and morphological changes are not sufficient to support
anchorage-dependent cell growth via non-integrin-mediated attachment. Cell
Biol. Int. 27,123-133.
·
Der-Shan Sun and Hsin-Hou Chang (2003).
Differential regulation of JNK in caspase-3 dependent apoptosis of MPP+
treated primary cortical neurons and untreated control cells. Cell
Biol. Int. 27, 769-777.
·
Jyh-Hwa Kau, Der-Shan Sun, Wei-Jern Tsai,
Huey-Fen Shyu, Hsin-Hsien
Huang, Hung-Chi Lin, and Hsin-Hou Chang* (2005).
Anti-platelet activities of anthrax lethal toxin are associated with suppressed
p42/44 and p38 mitogen-activated protein kinase pathways in the platelets. J.
Infect. Dis. 192, 1465-1474. (Impact factor: 5.99)
·
Szecheng J. Lo and Hsin-Hou
Chang (2005) Recombinant
snake disintegrins used for mammalian integrin study.
Toxin
Rev. 24,95-111.
·
Der-Shan Suna, Szecheng J. Lo, Chi-Hung Lin, Mei-Shiuan
Yu, Ching-Yi Huang, Yao-Fong Chen and Hsin-Hou Chang* (2005). Calcium oscillation and
phosphatidylinositol 3-kinase positively regulate integrin aIIbb3-mediated
outside-in signaling. J.
Biomed. Sci. 12, 321-333.
·
Jui-Chin Chang, Hsin-Hou Chang, Chien-Ting
Lin and Szecheng J. Lo. (2005). The integrin a6b1 modulation of PI3K
and Cdc42 activities induces dynamic filopodium
formation in human platelets. J.
Biomed. Sci. 12, 881-898.
·
Der-Shan
Sun, Szecheng J. Lo, Wei-Jern
Tsai, Chi-Hung Lin, Mei-Shiuan Yu, Yao-Fong Chen and Hsin-Hou Chang* (2005).
PI3-kinase is essential for ADP-stimulated integrin aIIbb3-mediated platelet
calcium oscillation, implications for P2Y receptor pathways in integrin aIIbb3-initiated signaling cross-talks.
J.
Biomed. Sci. 12, 937-948.
·
Hsin-Hou
Chang,
Mei-Fang Tsai, Chia-Pei Chung, Po-Kong Chen, Hsin-I
Hu, Jyh-Hwa Kau, Hsin-Hsien Huang, Hung-Chi Lin and Der-Shan Sun. (2006).
Single-step purification of recombinant anthrax lethal factor from periplasm of
Escherichia coli. J
Biotechnol 277-285.
·
Ming-Show
Wong, Wen-Chen Chu, Der-Shan Sun, Hsuan-Shun Huang, Jiann-Hwa Chen, Pei-Jane Tsai, Nien-Tsung
Lin, Mei-Shiuan Yu, Shang-Feng Hsu, Shih-Lien Wang,
and Hsin-Hou Chang* (2006). Visible-light-induced
bactericidal activity of a nitrogen-doped titanium photocatalyst against human
pathogens. Appl
Environ Microbiol 72,
6111-6116.
·
Hsin-Hou Chang* and Szecheng J. Lo (2007).
Snake venom disintegrin rhodostomin
served as a molecular tool to dissect the integrin function. Toxin
Reviews 26, 189-202.
·
Shu-Rung
Chang, Kung-Jiun Wang, Yan-Feng Lu, Lii-Jia Yang, Wei-Jie Chen,
Yu-Hsiang Lin, Hsin-Hou Chang, and
Shih-Lien Wang (2007). Characterization
of early gamma interferon (IFN-gamma) expression during murine listeriosis: identification of NK1.1(+)
CD11c(+) cells as the primary IFN-gamma-expressing cells. Infect
Immun 75, 1167-1176.
·
Der-Shan Sun, Chwan-Chuen
King, Hsuan-Shun Huang, Yung-Luen Shih,
Chin-Cheng Lee, Wei-Jern Tsai, Cheng-Ching Yu and Hsin-Hou
Chang* (2007). Antiplatelet autoantibodies
elicited by dengue virus non-structural protein 1 cause thrombocytopenia and
mortality in mice. J
Thromb Haemost 5, 2291-2299. (Impact factor: 5.72)
·
Chia-Liang
Cheng, Der-Shan Sun, Wen-Chen Chu, Yao-Hsuan Tseng,
Han-Chen Ho, Jia-Bin Wang, Pei-Hua Chung, Jiann-Hwa Chen, Pei-Jane Tsai, Nien-Tsung
Lin, Mei-Shiuan Yu and Hsin-Hou
Chang* (2009).
The effects of the bacterial interaction with visible-light responsive titania photocatalyst on the bactericidal performance. J Biomed Sci 16, 7.
·
Jyh-Hwa Kau, Der-Shan Sun, Hsin-Hsien
Huang, Ming-Show Wong, Hung-Chi Lin, Hsin-Hou
Chang* (2009). Role of visible light-activated photocatalyst on the reduction of
anthrax spore-induced mortality in mice. PLoS
ONE 4, e4167.
·
Ming-Show
Wong, Der-Shan Sun, Hsin-Hou
Chang* (2010).
Bactericidal Performance of Visible-Light Responsive Titania Photocatalyst with
Silver Nanostructures. PLoS
ONE 5, e10394
·
Hsuan-Shun Huang, Der-Shan
Sun, Te-Sheng Lien and Hsin-Hou
Chang* (2010).
Dendritic cells modulate platelet activity in IVIg-mediated amelioration of ITP
in mice. Blood,
116, 5002-9. (Impact factor: 10.45).
·
Jyh-Hwa Kau, Der-Shan Sun, Hsuan-Shun
Huang, Te-Sheng Lien, Hsin-Hsien
Huang, Hung-Chi Lin, Hsin-Hou
Chang* (2010).
Sublethal Doses of Anthrax Lethal Toxin on the Suppression of Macrophage
Phagocytosis PLoS
ONE 5, e14289.
·
Je-Wen
Liou, Ming-Hui Gu,
Yen-Kai Chen, Wen-Yi Chen, Yi-Cheng Chen, Yao-Hsuan
Tseng, Yu-Jiun Hung, Hsin-Hou
Chang* (2011). Visible Light Responsive Photocatalyst Induces Progressive
and Apical-Terminus Preferential Damages on Escherichia coli Surfaces. PLoS
ONE 6, e19982.
·
Wen-Ku
Chang, Der-Shan Sun, Hao Chan, Pai-Tsang
Huang, Wen-Shiang
Wu, Ching-Hui Lin, Yao-Hsuan Tseng, Yi-Hung Cheng, Chun-Chieh Tseng and Hsin-Hou Chang* (2011). Visible
light responsive core-shell structured In2O3@CaIn2O4
photocatalyst with superior bactericidal property and
biocompatibility. Nanomedicine:
Nanotechnology, Biology and Medicine, 2012; 8:609-17. (Impact factor: 6.16).
·
Kau JH, Shih YL, Lien TS, Lee CC,
Huang HH, Lin HC, Sun DS, Chang HH*. Activated protein C ameliorates Bacillus anthracis
lethal toxin-induced lethal pathogenesis in rats. J Biomed Sci 2012;
19:98.
·
Liou JW, Chang HH*. Bactericidal effects and
mechanisms of visible light-responsive titanium dioxide photocatalysts on
pathogenic bacteria. Arch Immunol Ther Exp (Warsz) 2012; 60:267-75 (Invited review).
·
Huang HS, Chang HH*. Platelets in Inflammation and
Immune Modulations: Functions Beyond Hemostasis. Arch Immunol Ther Exp (Warsz) 2012:443-51 (Invited review).
·
Lin YC, Tsai LW, Perevedentseva
E, Chang HH, Lin CH, Sun DS,
Lugovtsov AE, Priezzhev A, Mona J, Cheng CL. The influence of nanodiamond on
the oxygenation states and micro rheological properties of human red blood
cells in vitro. Journal of Biomedical Optics 2012;
17:101512.
·
Chen YL, Chen YS, Chan H, Tseng
YH, Yang SR, Tsai HY, Liu HY, Sun DS, Chang
HH*. The use of nanoscale visible
light-responsive photocatalyst TiO2-Pt for the elimination of soil-borne
pathogens. PLoS One 2012; 7:e31212.
·
Chang HH, Wang TP, Chen PK, Lin YY, Liao CH, Lin TK, Chiang YW,
Lin WB, Chiang CY, Kau JH, Huang HH, Hsu Hl, Liao CY, Sun DS. Erythropoiesis suppression
is associated with anthrax lethal toxin-mediated pathogenic progression. PLoS One 2013;
8:e71718.
·
Tseng YH, Sun DS, Wu WS, Chan H,
Syue MS, Ho HC, Chang HH*. Antibacterial performance of nanoscaled visible-light
responsive platinum-containing titania photocatalyst in vitro and in vivo. Biochim Biophys Acta 2013;
1830:3787-95.
·
Chen PK, Chang HH, Lin GL, Wang TP, Lai YL, Lin TK, Hsieh MC, Kau JH,
Huang HH, Hsu HL, Liao CY, Sun DS. Suppressive effects of anthrax lethal toxin
on megakaryopoiesis. PLoS One 2013; 8:e59512.
·
Chang HH, Chiang YW, Lin TK, Lin GL, Lin YY, Kau JH, Huang HH,
Hsu HL, Wang JH, Sun DS. Erythrocytic mobilization enhanced by the granulocyte
colony-stimulating factor is associated with reduced
anthrax-lethal-toxin-induced mortality in mice. PLoS One 2014;
9:e111149.
·
Chang HH, Chen PK, Lin GL, Wang CJ, Liao CH, Hsiao YC, Dong JH,
Sun DS. Cell adhesion as a novel approach to determining the cellular binding
motif on the severe acute respiratory syndrome coronavirus spike protein. J Virol Methods 2014;
201:1-6.
·
Chen YS, Shieh WJ, Goldsmith CS,
Metcalfe MG, Greer PW, Zaki SR, Chang
HH, Chan H, Chen YL. Alteration of the phenotypic and pathogenic
patterns of Burkholderia pseudomallei that persist in a soil environment. Am J Trop Med Hyg 2014;
90:469-79.
·
Sun DS, Chang YC, Lien TS, King
CC, Shih YL, Huang HS, Wang TY, Li CR, Lee CC, Hsu PN, Chang HH*. Endothelial Cell Sensitization
by Death Receptor Fractions of an Anti-Dengue Nonstructural Protein 1 Antibody
Induced Plasma Leakage, Coagulopathy, and Mortality in Mice. J Immunol 2015; 195:2743-53. (Impact factor: 4.922).
·
Lien TS, Sun DS, Chang CM, Wu CY,
Dai MS, Chan H, Wu WS, Su SH, Lin YY, Chang
HH*. Dengue virus and antiplatelet
autoantibodies synergistically induce haemorrhage through Nlrp3-inflammasome
and FcgammaRIII. Thromb Haemost 2015; 113:1060-70. (Impact
factor: 4.98)
·
Wong MS, Chen CW, Hsieh CC, Hung
SC, Sun DS, Chang HH*. Antibacterial property of Ag nanoparticle-impregnated
N-doped titania films under visible light. Sci Rep 2015;
5:11978. (Impact factor: 5.58)
·
Wu MS, Sun DS, Lin YC, Cheng CL,
Hung SC, Chen PK, Yang JH, Chang HH*. Nanodiamonds protect skin from ultraviolet B-induced
damage in mice. J Nanobiotechnology 2015; 13:35.
·
Sun DS, Lee PC, Kau JH, Shih YL, Huang
HH, Li CR, Lee CC, Wu YP, Chen KC, Chang
HH*. Acquired coagulant factor VIII
deficiency induced by Bacillus anthracis lethal toxin in mice. Virulence 2015; 6:466-75.
·
Hu HI, Chang HH, Sun DS. Differential regulation of caspase-2 in
MPP(+)-induced apoptosis in primary cortical neurons. Exp Cell Res 2015; 332:60-6.
·
Chen PK, Lin GL, Chang HH, Sun DS. Megakaryocytic
differentiation of mouse embryonic stem cells via coculture with immortalized
OP9 stromal cells. Exp
Cell Res 2015 Oct 7. pii:
S0014-4827(15)30108-7. doi: 10.1016/j.yexcr.2015.10.002. [Epub ahead of
print].
